Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178938 | 0.80 | NPC1 (0.54) | NPC1PLAUPARP1L3MBTL1KDM4E | |
| SCHEMBL9384191 | 0.78 | GRM5 (0.48) | NPC1L3MBTL1KDM4ECYP1A2BTK | |
| SCHEMBL4560363 | 0.77 | MKNK1 (0.50) | PARP1L3MBTL1KDM4ECYP1A2EIF4E | |
| SCHEMBL6616895 | 0.77 | PARP1 (0.50) | NPC1PLAUPARP1KDM4ECYP1A2 | |
| SCHEMBL31651965 | 0.76 | MKNK1 (0.42) | PARP1L3MBTL1KDM4EEIF4EIRAK4 | |
| SCHEMBL28271036 | 0.75 | NPC1 (0.74) | NPC1PLAUL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL4675603 | 0.75 | RAB9A (0.40) | PLAUL3MBTL1EIF4ERAB9AMKNK1 | |
| SCHEMBL30100563 | 0.75 | EIF4E (0.44) | PARP1L3MBTL1KDM4ECYP1A2EIF4E | |
| SCHEMBL935555 | 0.74 | CYP2A6 (0.49) | NPC1RAB9AMKNK2 | |
| SCHEMBL946785 | 0.74 | F7 (0.47) | BTKEIF4EIRAK4MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9211533-B2 | Organic metal complex and process for preparing amine compound | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2015-12-15 | — | — | US | disclosed |
| EP-2228377-B1 | Novel organometallic complex and process for preparing amine compound | KANTO KAGAKU (JP) | 2014-07-30 | — | — | EP | disclosed |
| US-20130338359-A1 | NOVEL ORGANIC METAL COMPLEX AND PROCESS FOR PREPARING AMINE COMPOUND | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2013-12-19 | — | — | US | disclosed |
| US-8481735-B2 | Organic metal complex and process for preparing amine compound | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20100234596-A1 | NOVEL ORGANIC METAL COMPLEX AND PROCESS FOR PREPARING AMINE COMPOUND | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2228377-A1 | Novel organometallic complex and process for preparing amine compound | Kanto Kagaku Kabushiki Kaisha (JP) | 2010-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338359-A1 | NOVEL ORGANIC METAL COMPLEX AND PROCESS FOR PREPARING AMINE COMPOUND | ODC1, AOC2, AOC1 | NPC1 2829/4885PLAU 3881/4885PARP1 1830/4885 |
| US-20100234596-A1 | NOVEL ORGANIC METAL COMPLEX AND PROCESS FOR PREPARING AMINE COMPOUND | ODC1, AOC2, AOC1 | NPC1 2829/4885PLAU 3881/4885PARP1 1830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.