Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.45 |
| ▸ | PPARA | Q07869 | 14/20 | 0.45 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177453 | 0.92 | ITGB3 (0.46) | PPARGPPARAITGB1ITGA5 | |
| SCHEMBL6177456 | 0.85 | ITGB3 (0.43) | PPARGPPARAITGB1ITGA5 | |
| SCHEMBL852663 | 0.75 | KMT2A (0.42) | — | |
| SCHEMBL854038 | 0.74 | ITGB3 (0.48) | ITGB1ITGA5 | |
| SCHEMBL853670 | 0.73 | NR1H2 (0.36) | LTA4H | |
| SCHEMBL13718712 | 0.73 | PPARG (0.82) | PPARGPPARA | |
| SCHEMBL6179307 | 0.72 | ITGB3 (0.56) | PPARAITGB1ITGA5 | |
| SCHEMBL6175338 | 0.72 | ITGB3 (0.49) | PPARGPPARAITGB1ITGA5 | |
| SCHEMBL852604 | 0.71 | KDM4E (0.42) | — | |
| SCHEMBL4919707 | 0.71 | ITGB1 (0.69) | ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061921-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-03-30 | — | — | EP | disclosed |
| US-20020147334-A1 | Vitronectin Receptor Antagonists | SMITHKLINE BEECHAM CORPORATION | 2002-10-10 | — | — | US | disclosed |
| EP-1061921-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999045927-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147334-A1 | Vitronectin Receptor Antagonists | ADGRF1, FN1, CALCR | PPARG 2449/4885PPARA 2296/4885LTA4H 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.