Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA9 | Q16790 | 7/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178131 | 0.97 | THRB (0.41) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL27689281 | 0.95 | THRB (0.42) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL8537817 | 0.92 | THRB (0.40) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL1935530 | 0.88 | ADRB2 (0.45) | THRBTSHRCA1CA2 | |
| SCHEMBL27693721 | 0.87 | THRB (0.40) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL6132365 | 0.83 | — | — | |
| SCHEMBL6176372 | 0.82 | ADRB2 (0.41) | THRBTSHRCA1CA2 | |
| SCHEMBL17416222 | 0.80 | THRB (0.44) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL981959 | 0.80 | THRB (0.44) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL262090 | 0.80 | THRB (0.44) | THRBTSHRMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1329364-C | Process for producing carbonic ester | ASAHI CHEMICAL CORP (JP) | 2007-08-01 | — | — | CN | disclosed |
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| CN-1608045-A | Process for producing carbonic ester | ASAHI KASEI CHEMICALS CORP (JP) | 2005-04-20 | — | — | CN | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0166389-B1 | NEW TETRACYCLO COMPOUNDS, A PROCESS FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-23 | — | — | EP | disclosed |
| US-4861774-A | Method of treating tumors using tetracyclo compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
| US-4743555-A | TETRACYCLO COMPOUND, ANTITUMOR, ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| US-4645765-A | MICROBIOCIDES, ANTITUMOR AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-02-24 | — | — | US | disclosed |
| EP-0166389-A1 | New tetracyclo compounds, a process for their production and a pharmaceutical composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | disclosed |