Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 11/20 | 0.61 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175791 | 0.84 | HTR4 (0.49) | HTR4 | |
| SCHEMBL6177813 | 0.80 | KCNH2 (0.58) | HTR4 | |
| Hydrochloric Acid SCHEMBL6761914 | 0.79 | KCNH2 (0.57) | HTR4 | |
| SCHEMBL5338077 | 0.76 | HTR4 (0.52) | HTR4DHODH | |
| SCHEMBL13579094 | 0.75 | DHODH (0.56) | HTR4DHODHHTR2A | |
| SCHEMBL5077332 | 0.72 | AURKA (0.58) | DHODHHTR2A | |
| SCHEMBL6175694 | 0.72 | NR4A2 (0.49) | HTR4 | |
| SCHEMBL6176072 | 0.72 | KCNH2 (0.52) | HTR4 | |
| SCHEMBL7348053 | 0.72 | HTR3A (0.51) | HTR4 | |
| SCHEMBL5074071 | 0.71 | PARP1 (0.48) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440071-B1 | IMIDAZOPYRIDINE COMPOUNDS AS 5-HT 4? RECEPTOR MODULATORS | PFIZER (US) | 2005-10-26 | — | — | EP | disclosed |