Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.40 |
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL6181993 | 0.94 | PPARG (0.52) | PPARGPPARACACNA1GKCNH2MME | |
| SCHEMBL6177022 | 0.90 | MEN1 (0.51) | PPARGPPARACACNA1GKCNH2CCNT1 | |
| SCHEMBL6178731 | 0.83 | PPARG (0.49) | PPARGPPARACACNA1GKCNH2CCNT1 | |
| SCHEMBL6176194 | 0.80 | MEN1 (0.52) | CACNA1GKCNH2MEN1ALDH1A1KMT2A | |
| SCHEMBL7759086 | 0.75 | PPARG (0.41) | PPARGPPARACACNA1GKCNH2CCNT1 | |
| SCHEMBL6180652 | 0.75 | PPARG (0.52) | PPARGPPARACACNA1GKCNH2CCNT1 | |
| SCHEMBL6181828 | 0.75 | MEN1 (0.45) | CACNA1GKCNH2MEN1ALDH1A1KMT2A | |
| Cyclohexane SCHEMBL6179896 | 0.74 | MEN1 (0.57) | CACNA1GKCNH2MEN1ALDH1A1KMT2A | |
| SCHEMBL6177540 | 0.73 | MEN1 (0.46) | MEN1ALDH1A1KMT2AHTR1A | |
| SCHEMBL6178409 | 0.72 | CCNT1 (0.54) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140830-B1 | ARYLPIPERIDINE AND ARYL-1,2,5,6-TETRAHYDROPYRIDINE AMIDE DERIVATIVES HAVING 5HT1A RECEPTOR ACTIVITY | WYETH CORP (US) | 2005-05-04 | — | — | EP | claimed |