Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.47 |
| ▸ | MEN1 | O00255 | 10/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487253 | 0.87 | KMT2A (0.43) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL5494434 | 0.84 | NPC1 (0.46) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL5494637 | 0.84 | TP53 (0.52) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL5778894 | 0.81 | RAB9A (0.47) | KMT2AMEN1HSP90AA1ALDH1A1LMNA | |
| SCHEMBL5778804 | 0.81 | RAB9A (0.47) | KMT2AMEN1HSP90AA1ALDH1A1LMNA | |
| SCHEMBL5494106 | 0.74 | NPC1 (0.59) | KMT2AMEN1HSP90AA1ALDH1A1LMNA | |
| SCHEMBL5781867 | 0.74 | RAB9A (0.61) | KMT2AMEN1HSP90AA1LMNARAB9A | |
| SCHEMBL7079006 | 0.73 | MEN1 (0.45) | KMT2AMEN1HSP90AA1ALDH1A1LMNA | |
| SCHEMBL27532202 | 0.71 | CCR2 (0.57) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL5493967 | 0.68 | TP53 (0.51) | KMT2AMEN1HSP90AA1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363897-B1 | ANTAGONISTS OF MCP-1 FUNCTION AND METHODS OF USE THEREOF | TELIK INC (US) | 2005-12-21 | — | — | EP | claimed |