Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | TNF | P01375 | 1/20 | 0.64 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | LIPE | Q05469 | 9/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GALR3 | O60755 | 1/20 | 0.53 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178349 | 0.87 | RAB9A (0.69) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| SCHEMBL31305896 | 0.87 | RAB9A (0.69) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| SCHEMBL1290892 | 0.87 | RAB9A (0.69) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| SCHEMBL6179437 | 0.86 | RAB9A (0.66) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| Hydrochloric Acid SCHEMBL1290991 | 0.86 | RAB9A (0.68) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| SCHEMBL3133529 | 0.85 | RAB9A (0.71) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| SCHEMBL6179298 | 0.84 | RAB9A (0.79) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| SCHEMBL3138983 | 0.83 | RAB9A (0.67) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| SCHEMBL6180370 | 0.82 | KCNQ3 (0.56) | RAB9AL3MBTL1NPC1GAAMAPK1 | |
| SCHEMBL3142668 | 0.82 | RAB9A (0.66) | RAB9AL3MBTL1NPC1TNFNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066261-B1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMA CO LTD (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-6511995-B1 | Inhibits collagen synthesis, which is useful for prophylaxis or treatment of fibrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |