Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561792 | 0.90 | TSHR (0.48) | ALDH1A1TRPA1TSHRSLC6A4CES2 | |
| SCHEMBL24917160 | 0.80 | SLC6A4 (0.55) | ALDH1A1SLC6A4MAOAMAOBHTR2C | |
| SCHEMBL3891569 | 0.79 | MAOA (0.62) | ALDH1A1TSHRSLC6A4MAOAMAOB | |
| SCHEMBL795030 | 0.79 | MAOA (0.62) | ALDH1A1TSHRSLC6A4MAOAMAOB | |
| SCHEMBL23277364 | 0.79 | MAOA (0.62) | ALDH1A1TSHRSLC6A4MAOAMAOB | |
| SCHEMBL3891151 | 0.79 | MAOA (0.62) | ALDH1A1TSHRSLC6A4MAOAMAOB | |
| SCHEMBL10707308 | 0.78 | CALM1 (0.60) | ALDH1A1SLC6A4MAOAMAOBHTR2C | |
| Diphenylsulfane SCHEMBL29001458 | 0.77 | SLC6A4 (0.47) | ALDH1A1TRPA1TSHRSLC6A4MAOA | |
| SCHEMBL5816143 | 0.76 | SLC6A4 (0.52) | ALDH1A1TSHRSLC6A4MAOAMAOB | |
| SCHEMBL5761245 | 0.76 | TSHR (0.59) | ALDH1A1TSHRSLC6A4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192590-B1 | Microwave-assisted formation of sulfonium photoacid generators | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-1092716-B1 | Derivatives of benzothiophenes, benzofurans and indoles, method for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-02-16 | — | — | EP | disclosed |
| US-6302837-B1 | ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 2001-10-16 | — | — | US | disclosed |
| EP-1092716-A2 | Derivatives of benzothiophenes, benzofurans and indoles, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-04-18 | — | — | EP | disclosed |
| US-4221803-A | FUNGICIDES, BACTERICIDES | RECORDATI, S.A. (CH) | 1980-09-09 | — | — | US | disclosed |
| US-4221803-A | FUNGICIDES, BACTERICIDES | RECORDATI, S.A. (CH) | 1980-09-09 | — | — | US | disclosed |