Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.66 |
| ▸ | CTSS | P25774 | 16/20 | 0.66 |
| ▸ | CTSL | P07711 | 15/20 | 0.66 |
| ▸ | CTSB | P07858 | 14/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5512597 | 1.00 | CTSK (0.66) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5522744 | 0.92 | CTSK (0.67) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6179388 | 0.92 | CTSK (0.67) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5520489 | 0.90 | CTSS (0.66) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5526388 | 0.90 | CTSS (0.66) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5520447 | 0.90 | CTSS (0.66) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5519064 | 0.90 | CTSS (0.66) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6181482 | 0.90 | CTSS (0.66) | CTSKCTSSCTSLCTSB | |
| Iodide SCHEMBL5526407 | 0.88 | CTSK (0.54) | CTSKCTSSCTSLCTSB | |
| Iodide SCHEMBL5526415 | 0.88 | CTSK (0.54) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537074-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA INC. (CA) | 2005-06-08 | — | — | EP | claimed |
| WO-2004022526-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2004-03-18 | — | — | WO | claimed |