Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | CD38 | P28907 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177750 | 0.87 | ADAMTS5 (0.44) | P2RY1MRGPRX4FFAR1PTGDR2NPC1 | |
| SCHEMBL7834257 | 0.85 | MRGPRX4 (0.50) | P2RY1MRGPRX4CD38FFAR1PTGDR2 | |
| SCHEMBL5205234 | 0.80 | TSHR (0.46) | P2RY1MRGPRX4CD38HTR2ASLC6A4 | |
| SCHEMBL5201777 | 0.79 | P2RY1 (0.43) | P2RY1MRGPRX4FFAR1HTR2ASLC6A4 | |
| SCHEMBL6176321 | 0.77 | FFAR1 (0.42) | FFAR1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6178866 | 0.76 | FFAR1 (0.44) | FFAR1PTGDR2TDP1 | |
| SCHEMBL5206113 | 0.74 | ADAMTS5 (0.48) | MRGPRX4FFAR1PTGDR2NPC1RAB9A | |
| SCHEMBL6177374 | 0.73 | F10 (0.44) | MRGPRX4PTGDR2SMN1; SMN2MAPTHPGD | |
| SCHEMBL20524098 | 0.73 | IDO1 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5350074 | 0.70 | PPARG (0.51) | CD38RPS6KB1PTGDR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |