Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176321 | 0.90 | FFAR1 (0.42) | ADAMTS5FFAR1ALDH1A1NPC1RAB9A | |
| SCHEMBL6178866 | 0.89 | FFAR1 (0.44) | PTGDR2FFAR1GAA | |
| SCHEMBL6180484 | 0.87 | P2RY1 (0.44) | PTGDR2FFAR1ALDH1A1NPC1RAB9A | |
| SCHEMBL5206113 | 0.85 | ADAMTS5 (0.48) | ADAMTS5PTGDR2FFAR1ALDH1A1NPC1 | |
| SCHEMBL6180089 | 0.81 | FFAR1 (0.54) | FFAR1 | |
| SCHEMBL5205774 | 0.80 | ADAMTS5 (0.40) | ADAMTS5PTGDR2FFAR1ALDH1A1MRGPRX4 | |
| SCHEMBL6174370 | 0.78 | CACNA1B (0.48) | ADAMTS5ALDH1A1GAAL3MBTL1 | |
| SCHEMBL5208318 | 0.78 | HDAC1 (0.43) | ADAMTS5PTGDR2FFAR1SMN1; SMN2 | |
| SCHEMBL7834277 | 0.76 | FFAR1 (0.44) | ADAMTS5FFAR1ALDH1A1RAB9AGAA | |
| SCHEMBL7834257 | 0.74 | MRGPRX4 (0.50) | PTGDR2FFAR1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |