Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 4/20 | 0.51 |
| ▸ | CCKBR | P32239 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177407 | 0.86 | KMT2A (0.40) | CCKARCCKBRALDH1A1MEN1KMT2A | |
| SCHEMBL6178926 | 0.82 | CCKBR (0.46) | CCKARCCKBRALDH1A1POLB | |
| SCHEMBL19949397 | 0.82 | CCKBR (0.46) | CCKARCCKBRALDH1A1POLB | |
| SCHEMBL6193195 | 0.82 | CCKBR (0.46) | CCKARCCKBRALDH1A1POLB | |
| SCHEMBL1394355 | 0.82 | CCKBR (0.46) | CCKARCCKBRALDH1A1POLB | |
| SCHEMBL541718 | 0.82 | CCKBR (0.46) | CCKARCCKBRALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL6178190 | 0.81 | CCKBR (0.45) | CCKARCCKBRALDH1A1POLB | |
| SCHEMBL6180501 | 0.81 | CCKBR (0.44) | CCKARCCKBRALDH1A1POLB | |
| SCHEMBL8946969 | 0.81 | CCKAR (0.61) | CCKARCCKBRALDH1A1MEN1KMT2A | |
| Oxalic Acid SCHEMBL6821965 | 0.80 | CCKBR (0.44) | CCKARCCKBRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |