Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182206 | 0.84 | DHODH (0.32) | DHODH | |
| SCHEMBL6181189 | 0.84 | NPC1 (0.35) | AOC3DHODHRAB9ANPC1TP53 | |
| SCHEMBL6179992 | 0.81 | NPC1 (0.37) | AOC3DHODHRAB9ANPC1TP53 | |
| SCHEMBL7575598 | 0.81 | DHODH (0.33) | DHODHPDE2AMEN1KMT2A | |
| SCHEMBL9117026 | 0.81 | DHODH (0.33) | DHODHPDE2A | |
| SCHEMBL7574755 | 0.80 | DHODH (0.33) | DHODHPDE2ACYP11B1CYP11B2 | |
| SCHEMBL7574569 | 0.79 | DHODH (0.32) | DHODHPDE2A | |
| SCHEMBL7573255 | 0.79 | DHODH (0.32) | DHODHPDE2AMEN1KMT2A | |
| SCHEMBL7577830 | 0.79 | DHODH (0.32) | DHODHPDE2AMEN1KMT2A | |
| SCHEMBL7575354 | 0.79 | DHODH (0.35) | DHODHPDE2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160244-B1 | Isoxazole derivatives and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2005-10-19 | — | — | EP | claimed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | claimed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | claimed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | claimed |
| EP-1160244-B1 | Isoxazole derivatives and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2005-10-19 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |