Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575598 | 0.89 | DHODH (0.33) | DHODHMEN1KMT2APDE2ANR1H4 | |
| SCHEMBL7573255 | 0.88 | DHODH (0.32) | DHODHMEN1KMT2APDE2ANR1H4 | |
| SCHEMBL7575354 | 0.87 | DHODH (0.35) | DHODHMEN1KMT2APDE2ANR1H4 | |
| SCHEMBL8891921 | 0.87 | ALDH1A1 (0.34) | NAMPTNR1H4 | |
| SCHEMBL8389669 | 0.86 | DHODH (0.34) | DHODHCXCR2MEN1KMT2ANAMPT | |
| SCHEMBL7574569 | 0.85 | DHODH (0.32) | DHODHMAPK1PDE2A | |
| SCHEMBL7572977 | 0.84 | PDE4D (0.35) | DHODHNR1H4 | |
| SCHEMBL7924451 | 0.84 | DHODH (0.34) | DHODHCXCR2MEN1KMT2ANAMPT | |
| SCHEMBL8488330 | 0.83 | PDE2A (0.36) | DHODHCXCR2MEN1KMT2ANAMPT | |
| SCHEMBL9115094 | 0.83 | DHODH (0.34) | DHODHCXCR2MEN1KMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | claimed |