Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934676 | 0.83 | MAOA (0.39) | MAOACES1TSHRMAOBBCHE | |
| SCHEMBL73596 | 0.77 | CES1 (0.52) | MAOACES1TSHRMAOBBCHE | |
| SCHEMBL51552 | 0.77 | MAOA (0.41) | MAOACES1TSHRMAOBBCHE | |
| SCHEMBL6787608 | 0.77 | ALDH1A1 (0.53) | MAOACES1TSHRBCHEKMT2A | |
| SCHEMBL11519242 | 0.76 | MAOA (0.40) | MAOACES1TSHRMAOBBCHE | |
| Water SCHEMBL3663798 | 0.76 | MAOA (0.40) | MAOACES1TSHRMAOBBCHE | |
| SCHEMBL11516879 | 0.76 | MAOA (0.40) | MAOACES1TSHRMAOBBCHE | |
| SCHEMBL4386410 | 0.76 | MAOA (0.40) | MAOACES1TSHRMAOBBCHE | |
| Hydrochloric Acid SCHEMBL8208617 | 0.76 | TSHR (0.44) | MAOACES1TSHRMAOBBCHE | |
| SCHEMBL11690364 | 0.76 | MAOA (0.40) | MAOACES1TSHRMAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3357 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | claimed |
| WO-2024127297-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | PFIZER INC. (US) | 2024-06-20 | — | — | WO | claimed |
| EP-4385979-A1 | MULTICYCLIC INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | claimed |
| EP-4385980-A1 | INDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | claimed |
| US-12012409-B2 | Bicyclic heterocycles as FGFR inhibitors | INCYTE CORPORATION (US) | 2024-06-18 | — | — | US | claimed |
| WO-2024118966-A1 | GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | TIGER BIOTHERAPEUTICS INC. (US) | 2024-06-06 | — | — | WO | claimed |
| WO-2024118960-A1 | GLUTARIMIDE-CONTAINING KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | TIGER BIOTHERAPEUTICS INC. (US) | 2024-06-06 | — | — | WO | claimed |
| US-11999699-B2 | Substituted pyrazole amides | Grünenthal GmbH (DE) | 2024-06-04 | — | — | US | claimed |
| US-11980633-B2 | Method for treating cancer using a combination of DNA-damaging agents and DNA-PK inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-05-14 | — | — | US | claimed |
| US-20240150334-A1 | HSD17B13 INHIBITORS AND/OR DEGRADERS | PFIZER INC. (US) | 2024-05-09 | — | — | US | claimed |
| EP-0489300-A2 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-10 | — | — | EP | claimed |
| WO-1992007850-A1 | NOVEL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | claimed |
| CN-1036759-A | Triazole derivative, its preparation method and its purposes as mycocide | SANKYO CO (JP) | 1989-11-01 | — | — | CN | claimed |
| EP-0332387-A1 | Triazole derivatives, their preparation and their use as fungicides | Sankyo Company Limited (JP) | 1989-09-13 | — | — | EP | claimed |
| US-4863948-A | Isoindolinone sulfonamide anti-arrhythmic agents | PFIZER, INC. (US) | 1989-09-05 | — | — | US | claimed |
| EP-0091726-B1 | 5-SUBSTITUTED 1,2,4-OXADIAZOLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-11-23 | — | — | EP | claimed |
| US-4560447-A | Electrolytic process for preparation of α-alkylated acetic acid derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1985-12-24 | — | — | US | claimed |
| US-4530843-A | Containing a heterocyclic ring | SYNTHELABO (FR) | 1985-07-23 | — | — | US | claimed |
| US-4455298-A | MOLLUSC EXTRACT | MCFARLANE STUART J (NZ) | 1984-06-19 | — | — | US | claimed |
| US-4367176-A | Esters of arylpropionic acids endowed with an anti-inflammatory activity and related pharmaceutical compositions | AUSONIA FARMACEUTICI S.R.L. (IT) | 1983-01-04 | — | — | US | claimed |