Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184233 | 0.93 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL7201012 | 0.85 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL8161932 | 0.84 | PTGS2 (0.36) | PTGS2PTGS1 | |
| SCHEMBL6169673 | 0.84 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6169468 | 0.83 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL6176550 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL6171284 | 0.80 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL6168380 | 0.80 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL6168950 | 0.80 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7203427 | 0.80 | PTGS2 (0.42) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045833-B1 | 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS | PFIZER (US) | 2005-11-02 | — | — | EP | disclosed |