Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 7/20 | 0.43 |
| ▸ | CCKAR | P32238 | 6/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181583 | 1.00 | CCKBR (0.43) | CCKBRCCKARSCN9AKMT2AL3MBTL1 | |
| SCHEMBL6178297 | 1.00 | CCKBR (0.43) | CCKBRCCKARSCN9AKMT2AL3MBTL1 | |
| SCHEMBL6182762 | 0.99 | SCN9A (0.43) | CCKBRCCKARSCN9AKMT2AL3MBTL1 | |
| SCHEMBL6178675 | 0.90 | ACE (0.42) | CCKBRSCN9AKMT2AL3MBTL1ACE | |
| SCHEMBL19966643 | 0.90 | SCN9A (0.42) | CCKBRSCN9AACE | |
| SCHEMBL6191073 | 0.89 | CCKBR (0.41) | CCKBRCCKARSCN9AKMT2AL3MBTL1 | |
| SCHEMBL6825710 | 0.89 | CCKBR (0.47) | CCKBRCCKARACE | |
| SCHEMBL6177390 | 0.89 | CCKBR (0.45) | CCKBRSCN9AKMT2AL3MBTL1ACE | |
| SCHEMBL6825712 | 0.89 | CCKBR (0.47) | CCKBRCCKARACE | |
| SCHEMBL7960849 | 0.88 | CCKBR (0.47) | CCKBRCCKARKMT2AL3MBTL1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |