Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19735046 | 0.84 | KDM4E (0.58) | KDM4EL3MBTL1HRH3SMN1; SMN2NPC1 | |
| SCHEMBL12431662 | 0.82 | KDM4E (0.59) | KDM4EL3MBTL1HRH3SMN1; SMN2NPC1 | |
| SCHEMBL951852 | 0.82 | KDM4E (0.59) | KDM4EL3MBTL1HRH3SMN1; SMN2NPC1 | |
| SCHEMBL951851 | 0.82 | KDM4E (0.59) | KDM4EL3MBTL1HRH3SMN1; SMN2NPC1 | |
| SCHEMBL31261054 | 0.82 | KDM4E (0.59) | KDM4EL3MBTL1HRH3SMN1; SMN2NPC1 | |
| SCHEMBL13621098 | 0.80 | KDM4E (0.58) | KDM4EL3MBTL1HRH3SMN1; SMN2NPC1 | |
| SCHEMBL662972 | 0.79 | KDM4E (0.61) | KDM4EL3MBTL1HRH3SMN1; SMN2NPC1 | |
| SCHEMBL15007 | 0.79 | KDM4E (0.61) | KDM4EL3MBTL1HRH3SMN1; SMN2NPC1 | |
| SCHEMBL9000467 | 0.78 | KDM4E (0.56) | KDM4EL3MBTL1HRH3SMN1; SMN2NPC1 | |
| SCHEMBL934192 | 0.78 | KDM4E (0.59) | KDM4EL3MBTL1HRH3SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521753-A2 | A PROCESS TO PREPARE PIOGLITAZONE VIA SEVERAL INTERMEDIATES. | CADILA HEALTHCARE LTD. (IN) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007490-A2 | A PROCESS TO PREPARE PIOGLITAZONE VIA SEVERAL INTERMEDIATES. | CADILA HEALTHCARE LIMITED (IN) | 2004-01-22 | — | — | WO | disclosed |