Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.77 |
| ▸ | ACACA | Q13085 | 14/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181556 | 0.92 | ACACB (0.80) | ACACBACACAKDM2B | |
| SCHEMBL6183505 | 0.91 | ACACB (0.84) | ACACBACACAKDM2B | |
| SCHEMBL976349 | 0.90 | ACACB (0.83) | ACACBACACAKDM2B | |
| SCHEMBL2622325 | 0.90 | ACACB (0.83) | ACACBACACAKDM2B | |
| SCHEMBL6183307 | 0.87 | ACACB (0.72) | ACACBACACAKDM2B | |
| SCHEMBL6183020 | 0.87 | ACACB (0.75) | ACACBACACAKMT2AKDM2B | |
| SCHEMBL3459079 | 0.87 | ACACB (1.00) | ACACBACACAADRA1AMEN1KMT2A | |
| SCHEMBL6185174 | 0.87 | ACACB (0.78) | ACACBACACAKDM2B | |
| SCHEMBL976549 | 0.87 | ACACB (1.00) | ACACBACACAADRA1AMEN1KMT2A | |
| SCHEMBL6182816 | 0.87 | ACACB (0.78) | ACACBACACAKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979741-B2 | Acetyl-CoA carboxylase inhibitors | PFIZER INC. (US) | 2005-12-27 | — | — | US | disclosed |
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | disclosed |