Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.37 |
| ▸ | PPARD | Q03181 | 7/20 | 0.37 |
| ▸ | PPARA | Q07869 | 7/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705612 | 0.93 | KMT2A (0.48) | KMT2AMAPTFFAR4FFAR1MEN1 | |
| SCHEMBL6216939 | 0.85 | FFAR1 (0.50) | FFAR4FFAR1FAAHGPR84 | |
| SCHEMBL6179030 | 0.78 | FFAR1 (0.53) | MAPTFFAR4FFAR1FAAHGPR84 | |
| SCHEMBL23094032 | 0.75 | GPR84 (0.38) | MAPTFFAR4FFAR1MAPK1GPR84 | |
| SCHEMBL20341607 | 0.75 | GPR84 (0.44) | MAPTFFAR4FFAR1GPR84PPARD | |
| SCHEMBL3472515 | 0.74 | GPR84 (0.41) | MAPTFFAR4FFAR1GPR84PPARD | |
| SCHEMBL5739513 | 0.72 | GPR84 (0.35) | KMT2AMAPTFFAR4FFAR1MEN1 | |
| SCHEMBL10768998 | 0.72 | CYP2C19 (0.36) | TSHRALDH1A1 | |
| SCHEMBL13875771 | 0.71 | CA2 (0.37) | KMT2AFFAR4FFAR1MEN1MAPK1 | |
| SCHEMBL7438181 | 0.71 | CA2 (0.37) | KMT2AFFAR4FFAR1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597223-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004067489-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |