⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719410 | 1.00 | — | — | |
| SCHEMBL19449189 | 0.92 | — | — | |
| SCHEMBL9978228 | 0.92 | — | — | |
| SCHEMBL1875891 | 0.92 | — | — | |
| SCHEMBL22641083 | 0.73 | TRPA1 (0.32) | — | |
| SCHEMBL19380565 | 0.73 | — | — | |
| SCHEMBL2333447 | 0.72 | — | — | |
| SCHEMBL28981368 | 0.69 | — | — | |
| SCHEMBL1362738 | 0.69 | — | — | |
| SCHEMBL1362739 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102630226-A | Entecavir synthesis method and intermediate compound thereof | AUSUN PHARMATECH CO LTD | 2012-08-08 | — | — | CN | claimed |
| EP-1499314-A1 | N-ACYL PIPERIDINE DERIVATIVES FOR USE AS MELANOCORTIN RECEPTOR LIGANDS IN THE TREATMENT OF FEEDING DISORDERS | The Procter & Gamble Company (US) | 2005-01-26 | — | — | EP | claimed |
| US-20040010010-A1 | Melanocortin receptor ligands | PROCTER & GAMBLE COMPANY, THE | 2004-01-15 | — | — | US | claimed |
| WO-2003092690-A1 | N-ACYL PIPERIDINE DERIVATIVES FOR USE AS MELANOCORTIN RECEPTOR LIGANDS IN THE TREATMENT OF FEEDING DISORDERS | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-13 | — | — | WO | claimed |
| EP-0247595-B1 | NEW AZAPHOSPHOLONES AND USE THEREOF | Studiengesellschaft Kohle mbH (DE) | 1992-01-02 | — | — | EP | claimed |
| US-4827067-A | Azaphospholenes and use thereof | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1989-05-02 | — | — | US | claimed |
| EP-2976076-B1 | TRAIL ENHANCERS FOR THE SELECTIVE KILLING OF CANCER CELLS | SCRIPPS RESEARCH INST (US) | 2020-03-04 | — | — | EP | disclosed |
| WO-2019150305-A1 | SUBSTITUTED QUINAZOLINE AND PYRIDOPYRIMIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2019-08-08 | — | — | WO | disclosed |
| CN-102630226-A | Entecavir synthesis method and intermediate compound thereof | AUSUN PHARMATECH CO LTD | 2012-08-08 | — | — | CN | disclosed |
| US-5712481-A | Process and apparatus for analysis of hydrocarbon species by near infrared spectroscopy | ASHLAND INC (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0247595-B1 | NEW AZAPHOSPHOLONES AND USE THEREOF | Studiengesellschaft Kohle mbH (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4912274-A | Azaphospholenes and use thereof | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1990-03-27 | — | — | US | disclosed |
| US-4900866-A | Azaphospholenes | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1990-02-13 | — | — | US | disclosed |
| US-4827067-A | Azaphospholenes and use thereof | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0247595-A2 | New azaphospholones and use thereof | Studiengesellschaft Kohle mbH (DE) | 1987-12-02 | — | — | EP | disclosed |