⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182086 | 1.00 | — | — | |
| SCHEMBL19449189 | 0.92 | — | — | |
| SCHEMBL9978228 | 0.92 | — | — | |
| SCHEMBL1875891 | 0.92 | — | — | |
| SCHEMBL22641083 | 0.73 | TRPA1 (0.32) | — | |
| SCHEMBL19380565 | 0.73 | — | — | |
| SCHEMBL2333447 | 0.72 | — | — | |
| SCHEMBL28981368 | 0.69 | — | — | |
| SCHEMBL1362738 | 0.69 | — | — | |
| SCHEMBL1362739 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247595-B1 | NEW AZAPHOSPHOLONES AND USE THEREOF | Studiengesellschaft Kohle mbH (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4912274-A | Azaphospholenes and use thereof | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1990-03-27 | — | — | US | disclosed |
| US-4900866-A | Azaphospholenes | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1990-02-13 | — | — | US | disclosed |
| US-4827067-A | Azaphospholenes and use thereof | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0247595-A2 | New azaphospholones and use thereof | Studiengesellschaft Kohle mbH (DE) | 1987-12-02 | — | — | EP | disclosed |