Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29479988 | 1.00 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL10513406 | 0.98 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL5838693 | 0.96 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B | |
| Fluoride Ion SCHEMBL1131318 | 0.96 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B | |
| Bromide SCHEMBL7878842 | 0.96 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL646564 | 0.81 | PNMT (0.39) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL7643263 | 0.80 | PNMT (0.44) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL524602 | 0.80 | PNMT (0.63) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL30103334 | 0.80 | PNMT (0.63) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL4389743 | 0.80 | PNMT (0.38) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 722 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362502-A | Method for preparing cycloolefin copolymer by adopting continuous flow integrated microreactor | 浙江大学 | 2024-01-09 | — | — | CN | claimed |
| US-9394388-B2 | Hybrid supported metallocene catalyst, method for preparing the same, and process for preparing polyolefin using the same | SK INNOVATION CO., LTD. (KR) | 2016-07-19 | — | — | US | claimed |
| US-20150025204-A1 | Hybrid Supported Metallocene Catalyst, Method for Preparing the Same, and Process for Preparing Polyolefin Using the Same | SK INNOVATION CO., LTD. (KR) | 2015-01-22 | — | — | US | claimed |
| WO-2013133595-A1 | HYBRID SUPPORTED METALLOCENE CATALYST, METHOD FOR PREPARING THE SAME, AND PROCESS FOR PREPARING POLYOLEFIN USING THE SAME | SK INNOVATION CO., LTD. (KR) | 2013-09-12 | — | — | WO | claimed |
| EP-1995258-B1 | Catalyst composition for polymerizing monomers | CHEVRON PHILLIPS CHEMICAL CO (US) | 2013-08-21 | — | — | EP | claimed |
| US-7763561-B2 | Compositions that can produce polymers | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2010-07-27 | — | — | US | claimed |
| US-7601665-B2 | Compositions that can produce polymers | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2009-10-13 | — | — | US | claimed |
| EP-1995258-A2 | Catalyst composition for polymerizing monomers | Chevron Phillips Chemical Company LP (US) | 2008-11-26 | — | — | EP | claimed |
| EP-1082355-B1 | CATALYST COMPOSITION FOR POLYMERIZING MONOMERS | CHEVRON PHILLIPS CHEMICAL CO (US) | 2008-10-15 | — | — | EP | claimed |
| US-20080058199-A1 | COMPOSITIONS THAT CAN PRODUCE POLYMERS | PHILLIPS PETROLEUM COMPANY (US) | 2008-03-06 | — | — | US | claimed |
| US-6316553-B1 | CONTACTING MONOMER WITH CATALYST WHICH IS IS PRODUCED BY CONTACTING ORGANOMETAL COMPOUND, TREATED SOLID OXIDE COMPOUND, ORGANOALUMINUM COMPOUND TO PRODUCE POLYMER | PHILLIPS PETROLEUM COMPANY | 2001-11-13 | — | — | US | claimed |
| US-6300271-B1 | OXIDES AND ORGANOALUMINUM COMPOUNDS | PHILLIPS PETROLEUM COMPANY | 2001-10-09 | — | — | US | claimed |
| EP-1082355-A1 | CATALYST COMPOSITION FOR POLYMERIZING MONOMERS | Phillips Petroleum Company (US) | 2001-03-14 | — | — | EP | claimed |
| US-6165929-A | Compositions that can produce polymers | PHILLIPS PETROLEUM COMPANY (US) | 2000-12-26 | — | — | US | claimed |
| US-6124231-A | Supported catalyst system, processes for its preparation, and its use for the polymerization of olefins | TARGOR GMBH (DE) | 2000-09-26 | — | — | US | claimed |
| US-6107230-A | COMPRISING CONTACTING AT LEAST ONE ORGANOMETAL COMPOUND AND AT LEAST ONE ORGANOALUMINUM COMPOUND WITH AT LEAST ONE TREATED SOLID OXIDE COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 2000-08-22 | — | — | US | claimed |
| WO-1999060033-A1 | CATALYST COMPOSITION FOR POLYMERIZING MONOMERS | PHILLIPS PETROLEUM COMPANY (US) | 1999-11-25 | — | — | WO | claimed |
| EP-0615981-B1 | Supported catalyst system, its preparation and its use in olefin polymerisation | TARGOR GMBH (DE) | 1998-05-06 | — | — | EP | claimed |
| EP-0610852-B1 | Process for preparing cyclo-olefin polymers | HOECHST AG (DE) | 1997-05-07 | — | — | EP | claimed |
| US-5545829-A | Process for preparing cycloolefin copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | claimed |