Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181243 | 0.75 | CHRNB4 (0.45) | CHRNB4CHRNA3CHRNB2CHRNA4MKNK1 | |
| SCHEMBL11466924 | 0.75 | CHRNB4 (0.50) | CHRNB4CHRNA3CHRNB2CHRNA4MKNK1 | |
| SCHEMBL11467927 | 0.75 | CHRNB4 (0.50) | CHRNB4CHRNA3CHRNB2CHRNA4MKNK1 | |
| SCHEMBL3123997 | 0.75 | CHRNB4 (0.60) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL14334241 | 0.75 | LTA4H (0.47) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL3117931 | 0.75 | IKBKB (0.47) | CHRNB4CHRNA3CHRNB2CHRNA4PIM1 | |
| SCHEMBL29007824 | 0.74 | CHRNB4 (0.60) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL5585295 | 0.73 | KDM4E (0.52) | CHRNB2CHRNA4 | |
| SCHEMBL11456174 | 0.72 | CHRNB4 (0.74) | CHRNB4CHRNA3CHRNB2CHRNA4PIM1 | |
| SCHEMBL11459124 | 0.72 | SLC6A2 (0.53) | CHRNB4CHRNA3CHRNB2CHRNA4PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513831-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Biovitrum AB (SE) | 2005-03-16 | — | — | EP | disclosed |
| WO-2004000830-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2003-12-31 | — | — | WO | disclosed |