SCHEMBL618305

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL617787	0.89	PTGS2 (0.68)	PTGS2ALDH1A1CYP3A4HSD17B10MEN1
	SCHEMBL617829	0.86	PTGS2 (0.57)	PTGS2ALDH1A1MAPTMEN1KMT2A
	SCHEMBL618566	0.85	PTGS2 (0.56)	PTGS2ALOX15MAPTMEN1KMT2A
	SCHEMBL615682	0.85	PTGS2 (0.56)	PTGS2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL616227	0.85	PTGS2 (0.56)	PTGS2ALDH1A1MAPTMEN1KMT2A
	SCHEMBL619458	0.85	PTGS2 (0.51)	PTGS2MAPTMEN1KMT2ATUBB4A
	SCHEMBL617226	0.84	PTGS2 (0.54)	PTGS2ALDH1A1CYP3A4MEN1KMT2A
	SCHEMBL618107	0.83	PTGS2 (0.51)	PTGS2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL617685	0.83	PTGS2 (0.53)	PTGS2MEN1KMT2ATUBB4ATUBB
	SCHEMBL616046	0.82	PTGS2 (0.56)	PTGS2LMNATUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.