Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183970 | 0.93 | TBXA2R (0.56) | TBXA2RTBXAS1 | |
| SCHEMBL6182420 | 0.89 | ABCB1 (0.50) | TBXA2RTBXAS1 | |
| SCHEMBL6184263 | 0.85 | ABCB1 (0.51) | TBXA2RTBXAS1 | |
| SCHEMBL6182991 | 0.83 | HTR2A (0.53) | TBXA2R | |
| Hydrochloric Acid SCHEMBL7225841 | 0.83 | HTR2A (0.52) | — | |
| SCHEMBL6186223 | 0.82 | TBXA2R (0.59) | TBXA2RTBXAS1 | |
| SCHEMBL6182962 | 0.81 | HTR2A (0.55) | — | |
| SCHEMBL6184164 | 0.81 | TBXA2R (0.58) | TBXA2RTBXAS1 | |
| SCHEMBL6182528 | 0.81 | TBXA2R (0.57) | TBXA2RTBXAS1 | |
| SCHEMBL6184251 | 0.81 | DRD1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | claimed |
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | claimed |
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | disclosed |
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |
| EP-1275641-A2 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-01-15 | — | — | EP | disclosed |