Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182420 | 0.96 | ABCB1 (0.50) | ABCB1TBXA2RHTR7TBXAS1 | |
| SCHEMBL6187752 | 0.91 | ABCB1 (0.61) | ABCB1HTR7HTR1AHTR2AHTR2C | |
| SCHEMBL6184857 | 0.87 | ABCB1 (0.61) | ABCB1HTR7HTR1AHTR2AHTR2C | |
| SCHEMBL6183970 | 0.86 | TBXA2R (0.56) | TBXA2RTBXAS1 | |
| SCHEMBL6183084 | 0.85 | TBXA2R (0.54) | TBXA2RTBXAS1 | |
| SCHEMBL7225705 | 0.84 | HTR2A (0.56) | HTR7HTR1AHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL7226979 | 0.84 | HTR2A (0.55) | HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL6185942 | 0.82 | ABCB1 (0.60) | ABCB1HTR1AHTR2A | |
| SCHEMBL6184588 | 0.81 | HTR2A (0.58) | HTR7HTR2AHTR6 | |
| SCHEMBL6182991 | 0.81 | HTR2A (0.53) | TBXA2RHTR7HTR1AHTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | disclosed |
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |
| EP-1275641-A2 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-01-15 | — | — | EP | disclosed |