Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 19/20 | 0.55 |
| ▸ | DRD2 | P14416 | 18/20 | 0.55 |
| ▸ | HTR7 | P34969 | 17/20 | 0.55 |
| ▸ | HTR6 | P50406 | 17/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184588 | 0.97 | HTR2A (0.58) | HTR2ADRD2HTR7HTR6DRD3 | |
| SCHEMBL7225536 | 0.88 | TBXA2R (0.42) | HTR2ADRD2HTR7HTR6 | |
| SCHEMBL6186018 | 0.85 | HTR2A (0.54) | HTR2ADRD2HTR6DRD3 | |
| SCHEMBL7235558 | 0.82 | HTR2A (0.49) | HTR2ADRD2HTR6DRD3 | |
| SCHEMBL6183970 | 0.82 | TBXA2R (0.56) | — | |
| SCHEMBL6184077 | 0.82 | HTR2A (0.58) | HTR2ADRD2HTR6DRD3 | |
| SCHEMBL6183084 | 0.81 | TBXA2R (0.54) | — | |
| SCHEMBL6182420 | 0.81 | ABCB1 (0.50) | HTR7 | |
| SCHEMBL6183391 | 0.79 | HTR2A (0.53) | HTR2ADRD2HTR6DRD3 | |
| SCHEMBL7112212 | 0.79 | HTR2A (0.56) | HTR2ADRD2HTR7HTR6DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | disclosed |
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |
| EP-1275641-A2 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-01-15 | — | — | EP | disclosed |