Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469703 | 0.87 | MTNR1A (0.36) | MTNR1AMTNR1BSTK17BALDH1A1MAPT | |
| SCHEMBL9237893 | 0.78 | MAPT (0.34) | PDE4DALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL7472213 | 0.76 | MAPT (0.35) | MTNR1AMTNR1BSTK17BALDH1A1MAPT | |
| SCHEMBL7465160 | 0.75 | MAPT (0.33) | MTNR1AMTNR1BALDH1A1MAPTKMT2A | |
| SCHEMBL6184513 | 0.74 | STK17B (0.32) | MTNR1AMTNR1BSTK17BMAPTKMT2A | |
| SCHEMBL6184518 | 0.74 | STK17B (0.32) | MTNR1AMTNR1BSTK17BMAPTKMT2A | |
| SCHEMBL9239772 | 0.73 | KDM4E (0.35) | MTNR1AMTNR1BALDH1A1MAPTHSD17B10 | |
| SCHEMBL7466991 | 0.72 | DYRK1A (0.32) | PDE4DALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL7464239 | 0.69 | DHODH (0.32) | MTNR1AMTNR1BSTK17BPDE4DALDH1A1 | |
| SCHEMBL8388765 | 0.68 | PDE4D (0.36) | PDE4DALDH1A1MAPTHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160244-B1 | Isoxazole derivatives and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2005-10-19 | — | — | EP | disclosed |
| EP-0636622-B1 | Isoxazole derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |