Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472213 | 0.86 | MAPT (0.35) | MAPTSMN1; SMN2RECQLALDH1A1KMT2A | |
| SCHEMBL7469824 | 0.80 | TSHR (0.42) | ALDH1A1KMT2A | |
| SCHEMBL7464261 | 0.79 | KMT2A (0.34) | MAPTALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7464266 | 0.79 | TSHR (0.41) | ALDH1A1KMT2A | |
| SCHEMBL7466592 | 0.78 | CA12 (0.40) | MAPTSMN1; SMN2RECQLALDH1A1KMT2A | |
| SCHEMBL7467609 | 0.78 | — | — | |
| SCHEMBL6183154 | 0.75 | MTNR1A (0.36) | MAPTALDH1A1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7469703 | 0.74 | MTNR1A (0.36) | MAPTSMN1; SMN2ALDH1A1KMT2AMTNR1A | |
| SCHEMBL7469191 | 0.73 | HCRTR2 (0.32) | — | |
| SCHEMBL8389663 | 0.70 | SMN1; SMN2 (0.36) | MAPTSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636622-B1 | Isoxazole derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |