⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619486 | 0.75 | — | — | |
| SCHEMBL826097 | 0.60 | — | — | |
| SCHEMBL197588 | 0.60 | — | — | |
| SCHEMBL19743487 | 0.59 | TRPA1 (0.33) | — | |
| SCHEMBL17653495 | 0.59 | HDAC4 (0.34) | — | |
| SCHEMBL11952530 | 0.59 | HDAC4 (0.34) | — | |
| SCHEMBL8521408 | 0.59 | TRPA1 (0.33) | — | |
| SCHEMBL20542554 | 0.59 | HDAC4 (0.34) | — | |
| SCHEMBL10997116 | 0.59 | — | — | |
| SCHEMBL2194008 | 0.59 | HDAC4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169482-B1 | PROCESS FOR THE PREPARATION OF 5,6-DIHYDRO-2H-THIOPYRAN-3-CARBOXALDEHYDES | BASF Aktiengesellschaft (DE) | 1989-01-18 | — | — | EP | claimed |
| US-4670567-A | Process for the preparation of 5,6-dihydro-2H-thiopyran-3-carboxaldehyde derivatives wherein the reactions are conducted in a high boiling mineral oil without a catalyst | BASF AKTIENGESELLSCHAFT (DE) | 1987-06-02 | — | — | US | claimed |
| EP-0141960-B1 | METHOD FOR THE PREPARATION OF TETRAHYDROTHIOPYRAN-3-CARBOXALDEHYDES | BASF Aktiengesellschaft (DE) | 1987-05-06 | — | — | EP | claimed |
| US-4629799-A | Preparation of 3-formyltetrahydrothiopyrans | BASF AKTIENGESELLSCHAFT (DE) | 1986-12-16 | — | — | US | claimed |
| EP-0141960-A1 | Method for the preparation of tetrahydrothiopyran-3-carboxaldehydes | BASF Aktiengesellschaft (DE) | 1985-05-22 | — | — | EP | claimed |
| EP-4494466-A1 | SULFUR-CONTAINING COMPOUNDS AND USE THEREOF | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2025-01-22 | — | — | EP | disclosed |
| CN-113024506-B | Process for preparing 3-formyltetrahydrothiopyran compounds | 合肥工业大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-113024506-A | Process for preparing 3-formyltetrahydrothiopyran compounds | 合肥工业大学 | 2021-06-25 | — | — | CN | disclosed |
| US-10125338-B2 | Flavor and fragrance compositions containing thiopyran-carbaldehyde | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2018-11-13 | — | — | US | disclosed |
| EP-3025591-B1 | FLAVOR AND FRAGRANCE COMPOSITIONS CONTAINING THIOPYRAN-CARBALDEHYDE | INT FLAVORS & FRAGRANCES INC (US) | 2017-10-18 | — | — | EP | disclosed |
| EP-3025591-B1 | FLAVOR AND FRAGRANCE COMPOSITIONS CONTAINING THIOPYRAN-CARBALDEHYDE | INT FLAVORS & FRAGRANCES INC (US) | 2017-10-18 | — | — | EP | disclosed |
| US-20170051232-A1 | FLAVOR AND FRAGRANCE COMPOSITIONS CONTAINING THIOPYRAN-CARBALDEHYDE | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2017-02-23 | — | — | US | disclosed |
| EP-0141960-B1 | METHOD FOR THE PREPARATION OF TETRAHYDROTHIOPYRAN-3-CARBOXALDEHYDES | BASF Aktiengesellschaft (DE) | 1987-05-06 | — | — | EP | disclosed |
| US-4629799-A | Preparation of 3-formyltetrahydrothiopyrans | BASF AKTIENGESELLSCHAFT (DE) | 1986-12-16 | — | — | US | disclosed |
| US-4629799-A | Preparation of 3-formyltetrahydrothiopyrans | BASF AKTIENGESELLSCHAFT (DE) | 1986-12-16 | — | — | US | disclosed |
| EP-0169482-A2 | Process for the preparation of 5,6-dihydro-2H-thiopyran-3-carboxaldehydes | BASF Aktiengesellschaft (DE) | 1986-01-29 | — | — | EP | disclosed |
| EP-0169482-A2 | Process for the preparation of 5,6-dihydro-2H-thiopyran-3-carboxaldehydes | BASF Aktiengesellschaft (DE) | 1986-01-29 | — | — | EP | disclosed |
| EP-0169482-A2 | Process for the preparation of 5,6-dihydro-2H-thiopyran-3-carboxaldehydes | BASF Aktiengesellschaft (DE) | 1986-01-29 | — | — | EP | disclosed |
| EP-0141960-A1 | Method for the preparation of tetrahydrothiopyran-3-carboxaldehydes | BASF Aktiengesellschaft (DE) | 1985-05-22 | — | — | EP | disclosed |
| EP-0141960-A1 | Method for the preparation of tetrahydrothiopyran-3-carboxaldehydes | BASF Aktiengesellschaft (DE) | 1985-05-22 | — | — | EP | disclosed |