Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | GLS | O94925 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19427715 | 0.92 | HSD17B10 (0.63) | HIF1AMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL19427517 | 0.86 | HSD17B10 (0.60) | HIF1AMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL31393812 | 0.84 | MEN1 (0.76) | HIF1AMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL8049389 | 0.84 | MEN1 (0.76) | HIF1AMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL10340313 | 0.83 | ALDH1A1 (0.65) | HIF1AMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL19427716 | 0.83 | KMT2A (0.69) | MEN1KMT2ATSHRHSD17B10ALDH1A1 | |
| SCHEMBL19427444 | 0.82 | ALDH1A1 (0.73) | MEN1KMT2AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL15643259 | 0.82 | KMT2A (0.59) | HIF1AMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL13485784 | 0.81 | HSD17B10 (0.69) | HIF1AMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL8639959 | 0.81 | KDM4E (0.60) | MEN1KMT2ATSHRHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562919-A1 | PHENYLALKYL AND PYRIDYLALKYL PIPERAZINE DERIVATIVES | Warner-Lambert Company LLC (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004041793-A1 | PHENYLALKYL AND PYRIDYLALKYL PIPERAZINE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2004-05-21 | — | — | WO | disclosed |