Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.67 |
| ▸ | CLK1 | P49759 | 2/20 | 0.67 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.67 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.67 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.67 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.67 |
| ▸ | NAT1 | P18440 | 6/20 | 0.54 |
| ▸ | MYC | P01106 | 2/20 | 0.54 |
| ▸ | MAX | P61244 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224564 | 0.93 | CSNK2A2 (0.64) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL6224561 | 0.93 | CSNK2A2 (0.64) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL12975558 | 0.89 | GSK3B (0.69) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL2880312 | 0.89 | GSK3B (0.69) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL30250232 | 0.83 | GSK3B (0.77) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL5342146 | 0.81 | CSNK2A2 (0.61) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL5342147 | 0.81 | CSNK2A2 (0.61) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL16762284 | 0.80 | DYRK1A (1.00) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL13196839 | 0.80 | DYRK1A (1.00) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL16762283 | 0.80 | DYRK1A (1.00) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581529-A1 | BENZOXAZINES AND DERIVATIVES THEREOF AS INHIBITORS OF PI3KS | WARNER-LAMBERT COMPANY (US) | 2005-10-05 | — | — | EP | disclosed |
| US-20040138199-A1 | Benzoxazines and derivatives thereof as therapeutic agents | GOGLIOTTI ROCCO DEAN (US) | 2004-07-15 | — | — | US | disclosed |
| WO-2004056820-A1 | BENZOXAZINES AND DERIVATIVES THEREOF AS INHIBITORS OF PI3KS | WARNER-LAMBERT COMPANY LLC (US) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138199-A1 | Benzoxazines and derivatives thereof as therapeutic agents | XDH, TBXA2R, TBXAS1 | CSNK2A2 1130/4885CLK1 602/4885CSNK2B 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.