Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.55 |
| ▸ | CCND1 | P24385 | 1/20 | 0.55 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183753 | 1.00 | CCNB2 (0.55) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8710177 | 0.87 | CCNB2 (0.66) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8710180 | 0.87 | CCNB2 (0.66) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL6184123 | 0.86 | PTGER4 (0.61) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL6184117 | 0.86 | PTGER4 (0.61) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL12379205 | 0.79 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL9857485 | 0.76 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL9871990 | 0.76 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL7293378 | 0.76 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL9857489 | 0.76 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | disclosed |
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |
| EP-1275641-A2 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-01-15 | — | — | EP | disclosed |