Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 8/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183774 | 0.88 | KMT2A (0.51) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL14148998 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3470444 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL19868916 | 0.82 | SMN1; SMN2 (0.47) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL13549768 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4099273 | 0.75 | KDM4E (0.66) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4099271 | 0.75 | KDM4E (0.66) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL17793846 | 0.75 | ALDH1A1 (0.46) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7029625 | 0.74 | HSP90AB1 (0.56) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4409938 | 0.74 | ALDH1A1 (0.54) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |