Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183937 | 0.88 | KDM4E (0.53) | KMT2AMEN1KDM4EALDH1A1ALOX12 | |
| SCHEMBL3469723 | 0.84 | KMT2A (0.58) | KMT2AMEN1KDM4EALDH1A1ALOX12 | |
| SCHEMBL19868916 | 0.82 | SMN1; SMN2 (0.47) | KMT2AMEN1ALDH1A1ALOX12MAPT | |
| SCHEMBL27341471 | 0.80 | ALDH1A1 (0.48) | KMT2AMEN1KDM4EALDH1A1ALOX12 | |
| SCHEMBL4095316 | 0.75 | KMT2A (0.66) | KMT2AMEN1KDM4EALDH1A1ALOX12 | |
| SCHEMBL4095314 | 0.75 | KMT2A (0.66) | KMT2AMEN1KDM4EALDH1A1ALOX12 | |
| SCHEMBL4375388 | 0.74 | TP53 (0.46) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL14148998 | 0.73 | KDM4E (0.59) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL3470444 | 0.72 | KDM4E (0.58) | KMT2AMEN1KDM4EALDH1A1ALOX12 | |
| SCHEMBL26173841 | 0.71 | MPO (0.49) | KMT2AMEN1KDM4EALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |