Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 8/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185063 | 0.89 | AKT2 (0.43) | SLC6A4SLC6A3KDM4EPTPN11AKT1 | |
| SCHEMBL6183465 | 0.89 | PTPN11 (0.40) | DPP4KDM4EPTPN11ALDH1A1 | |
| SCHEMBL6183516 | 0.88 | KMT2A (0.45) | KCNH2ALDH1A1TP53NPY1R | |
| SCHEMBL6186273 | 0.87 | KDM4E (0.48) | SLC6A4DPP4DPP9DPP8KDM4E | |
| SCHEMBL14549641 | 0.79 | DPP4 (0.64) | SLC6A4SLC6A3DPP4KCNH2DPP9 | |
| SCHEMBL4806920 | 0.79 | MEN1 (0.46) | SLC6A4SLC6A3DPP4KCNH2DPP9 | |
| Hydrochloric Acid SCHEMBL14482846 | 0.79 | DPP4 (0.62) | SLC6A4SLC6A3DPP4KCNH2DPP9 | |
| Hydrochloric Acid SCHEMBL14482848 | 0.79 | DPP4 (0.62) | SLC6A4SLC6A3DPP4KCNH2DPP9 | |
| Hydrochloric Acid SCHEMBL14483530 | 0.79 | DPP4 (0.62) | SLC6A4SLC6A3DPP4KCNH2DPP9 | |
| SCHEMBL6185472 | 0.78 | KDM4E (0.48) | SLC6A4KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513835-A1 | PIPERAZINYLACYLPIPERIDINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003104225-A1 | PIPERAZINYLACYLPIPERIDINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2003-12-18 | — | — | WO | disclosed |