Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183977 | 0.88 | SLC6A4 (0.42) | NPY1RKCNH2TP53ALDH1A1 | |
| SCHEMBL6183465 | 0.87 | PTPN11 (0.40) | LMNAL3MBTL1MAPTACHEALDH1A1 | |
| SCHEMBL6186273 | 0.85 | KDM4E (0.48) | NPY1RLMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL6185063 | 0.82 | AKT2 (0.43) | MAPTACHE | |
| SCHEMBL4814964 | 0.81 | ALDH1A1 (0.48) | KMT2AMEN1TSHRNPY1RLMNA | |
| SCHEMBL6185472 | 0.77 | KDM4E (0.48) | LMNAL3MBTL1MAPTACHEALDH1A1 | |
| SCHEMBL6183506 | 0.75 | KDM4E (0.47) | NPY1RLMNAL3MBTL1MAPTACHE | |
| SCHEMBL15056945 | 0.69 | KMT2A (0.59) | KMT2AOPRD1ALDH1A1SOAT1 | |
| SCHEMBL4812357 | 0.69 | ALDH1A1 (0.61) | KMT2AMEN1TSHRNPY1ROPRD1 | |
| SCHEMBL6153163 | 0.68 | SOAT1 (0.57) | NPY1ROPRD1KCNH2MAPTSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513835-A1 | PIPERAZINYLACYLPIPERIDINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003104225-A1 | PIPERAZINYLACYLPIPERIDINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2003-12-18 | — | — | WO | disclosed |