Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.67 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | BCR | P11274 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186103 | 0.94 | SRC (0.70) | SRCABL1BCRCYP3A4CYP2D6 | |
| SCHEMBL6184864 | 0.93 | SRC (0.65) | SRCABL1BCRCYP3A4CYP2D6 | |
| SCHEMBL6187929 | 0.85 | SRC (0.70) | SRCABL1BCR | |
| SCHEMBL6184230 | 0.84 | SRC (0.68) | SRCABL1BCRCYP3A4CYP2D6 | |
| SCHEMBL5255289 | 0.83 | SRC (0.58) | SRCABL1BCR | |
| SCHEMBL6183032 | 0.83 | SRC (0.61) | SRCABL1BCR | |
| SCHEMBL5255493 | 0.83 | SRC (0.58) | SRCABL1BCRKCNH2 | |
| SCHEMBL6185291 | 0.83 | SRC (0.70) | SRCABL1BCR | |
| SCHEMBL6182900 | 0.83 | SRC (0.93) | SRCABL1BCRCYP3A4CYP2D6 | |
| SCHEMBL6183128 | 0.83 | SRC (0.55) | SRCABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499594-B1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED-3-QUINOLINE AND 3-QUINOL-4-ONE CARBONITRILES | WYETH CORP (US) | 2005-08-17 | — | — | EP | claimed |