Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.65 |
| ▸ | ABL1 | P00519 | 4/20 | 0.55 |
| ▸ | BCR | P11274 | 4/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | STK25 | O00506 | 1/20 | 0.51 |
| ▸ | CIT | O14578 | 1/20 | 0.51 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.51 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | CASK | O14936 | 1/20 | 0.51 |
| ▸ | GAK | O14976 | 1/20 | 0.51 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.51 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.51 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | ULK1 | O75385 | 1/20 | 0.51 |
| ▸ | PAK3 | O75914 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184449 | 0.93 | SRC (0.67) | SRCABL1BCRKCNH2CYP3A4 | |
| SCHEMBL6186103 | 0.92 | SRC (0.70) | SRCABL1BCRKCNH2CYP3A4 | |
| SCHEMBL6187929 | 0.85 | SRC (0.70) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6184230 | 0.84 | SRC (0.68) | SRCABL1BCRKCNH2STK25 | |
| SCHEMBL6182389 | 0.84 | SRC (0.91) | SRCABL1BCRKCNH2STK25 | |
| SCHEMBL5255493 | 0.83 | SRC (0.58) | SRCABL1BCRKCNH2STK25 | |
| SCHEMBL6184673 | 0.82 | SRC (0.60) | SRCABL1BCRABL2 | |
| SCHEMBL6183032 | 0.82 | SRC (0.61) | SRCABL1BCR | |
| SCHEMBL5255289 | 0.82 | SRC (0.58) | SRCABL1BCRABL2 | |
| SCHEMBL6185291 | 0.81 | SRC (0.70) | SRCABL1BCRFYNABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499594-B1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED-3-QUINOLINE AND 3-QUINOL-4-ONE CARBONITRILES | WYETH CORP (US) | 2005-08-17 | — | — | EP | claimed |