SCHEMBL618456

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL617751	0.94	POLB (0.55)	MAPK1POLBHTTEPHB4ABCB1
	SCHEMBL615932	0.87	PTGS2 (0.52)	PTGS2HSD17B10PDGFRBBRAF
	SCHEMBL10188830	0.87	SLC2A1 (0.46)	MAPK1PTGS2KDM4EHSD17B10PDGFRB
	SCHEMBL617852	0.84	PTGS2 (0.51)	PTGS2HSD17B10PDGFRBBRAF
	SCHEMBL616937	0.83	PTGS2 (0.70)	PTGS2EPHB4
	SCHEMBL616273	0.82	PTGS2 (0.72)	PTGS2EPHB4
	SCHEMBL617700	0.81	FYN (0.54)	PTGS2EPHB4
	SCHEMBL616176	0.81	PTGS2 (0.54)	PTGS2KDM4EALDH1A1
	SCHEMBL617838	0.81	FYN (0.55)	PTGS2PDGFRBBRAFKDR
	SCHEMBL617567	0.81	PTGS2 (0.54)	PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.