Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 17/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 17/20 | 0.51 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21038725 | 0.90 | SLC6A2 (0.55) | SLC6A2SLC6A4 | |
| SCHEMBL25619700 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| Fumaric Acid SCHEMBL5995869 | 0.87 | SLC6A2 (0.59) | SLC6A2SLC6A4 | |
| SCHEMBL1087321 | 0.82 | SLC6A4 (0.49) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL628428 | 0.81 | ADH1A (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL6187922 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4 | |
| SCHEMBL23377075 | 0.80 | SLC6A4 (0.49) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL1087881 | 0.80 | SLC6A2 (0.56) | SLC6A2SLC6A4 | |
| SCHEMBL255044 | 0.80 | SLC6A2 (0.49) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL15108737 | 0.78 | SLC6A2 (0.40) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110467637-B | Bisaminyl chloropyrimidine compound containing phosphine oxide substituted aniline, preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2022-02-18 | — | — | CN | disclosed |
| EP-1569905-A2 | INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004052858-A2 | INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |