Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 3/20 | 0.38 |
| ▸ | ADH1C | P00326 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22200610 | 0.90 | SLC6A2 (0.37) | ADH1AADH1CMEN1KMT2ASLC6A2 | |
| SCHEMBL14160972 | 0.82 | ALDH1A1 (0.41) | ADH1AADH1CALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL23653664 | 0.81 | SLC6A2 (0.33) | SLC6A2SLC6A4CHI3L1 | |
| SCHEMBL6184745 | 0.81 | SLC6A2 (0.51) | SLC6A2SLC6A4 | |
| SCHEMBL21214484 | 0.79 | CHI3L1 (0.37) | MEN1KMT2ASLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL24996686 | 0.79 | MEN1 (0.42) | ADH1AADH1CMEN1KMT2AALDH1A1 | |
| SCHEMBL10241835 | 0.79 | LPAR3 (0.37) | ADH1AADH1CMEN1KMT2AALDH1A1 | |
| SCHEMBL8916450 | 0.79 | ADH1A (0.50) | ADH1AADH1CMEN1KMT2ADRD3 | |
| SCHEMBL24951489 | 0.78 | SLC6A2 (0.37) | SLC6A2SLC6A4CHI3L1KCNH2 | |
| SCHEMBL16348742 | 0.78 | ACHE (0.32) | ADH1ASLC6A2SLC6A4CHI3L1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |