Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | ACACA | Q13085 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182658 | 0.94 | CYP2C9 (0.55) | CYP2C9ACACBACACATRPV1KDM4E | |
| SCHEMBL6184042 | 0.90 | ACACB (0.53) | CYP2C9ACACBACACATRPV1KDM4E | |
| SCHEMBL6184044 | 0.85 | CYP2C9 (0.58) | CYP2C9ACACBACACAKDM4ESMN1; SMN2 | |
| SCHEMBL6182624 | 0.84 | CYP2C9 (0.57) | CYP2C9ACACBACACAKDM4ESMN1; SMN2 | |
| SCHEMBL6184046 | 0.83 | ACACB (0.66) | CYP2C9ACACBACACATRPV1KDM4E | |
| SCHEMBL6185621 | 0.80 | CYP2C9 (0.73) | CYP2C9ACACBACACATRPV1KDM4E | |
| SCHEMBL6185309 | 0.80 | ACACB (0.53) | CYP2C9ACACBACACATRPV1KDM4E | |
| SCHEMBL6182731 | 0.79 | ACACB (0.56) | CYP2C9ACACBACACAKDM4ESMN1; SMN2 | |
| SCHEMBL6184436 | 0.78 | ACACB (0.53) | CYP2C9ACACBACACAKDM4ESMN1; SMN2 | |
| SCHEMBL6184040 | 0.77 | CYP2C9 (0.72) | CYP2C9ACACBACACAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979741-B2 | Acetyl-CoA carboxylase inhibitors | PFIZER INC. (US) | 2005-12-27 | — | — | US | disclosed |
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | disclosed |
| US-20030187254-A1 | Acetyl-CoA carboxylase inhibitors | PFIZER INC. | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187254-A1 | Acetyl-CoA carboxylase inhibitors | ACACA, ACACB, ACAT1 | CYP2C9 1250/4885ACACB 2/4885ACACA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.