Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15314381 | 0.82 | MCOLN3 (0.52) | MCOLN3HSD11B1BDKRB1ALDH1A1L3MBTL1 | |
| SCHEMBL4033271 | 0.79 | MCOLN3 (0.55) | MCOLN3HSD11B1BDKRB1ALDH1A1L3MBTL1 | |
| SCHEMBL3439979 | 0.78 | MCOLN3 (0.55) | MCOLN3HSD11B1BDKRB1ALDH1A1L3MBTL1 | |
| SCHEMBL4027618 | 0.78 | MCOLN3 (0.54) | MCOLN3HSD11B1ALDH1A1ITGAVTSHR | |
| SCHEMBL7847967 | 0.77 | MCOLN3 (0.56) | MCOLN3HSD11B1BDKRB1ALDH1A1L3MBTL1 | |
| SCHEMBL12010352 | 0.77 | MCOLN3 (0.56) | MCOLN3HSD11B1BDKRB1ALDH1A1L3MBTL1 | |
| SCHEMBL5111158 | 0.76 | MCOLN3 (0.52) | MCOLN3HSD11B1BDKRB1ALDH1A1L3MBTL1 | |
| SCHEMBL2642338 | 0.76 | MCOLN3 (0.67) | MCOLN3HSD11B1ALDH1A1TSHRPGR | |
| SCHEMBL5393186 | 0.75 | MCOLN3 (0.51) | MCOLN3HSD11B1BDKRB1ALDH1A1L3MBTL1 | |
| SCHEMBL5118895 | 0.75 | MCOLN3 (0.51) | MCOLN3HSD11B1BDKRB1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521744-A1 | ARYLSULPHONAMIDE DERIVATIVES AND USE THEREOF AS B1 BRADYKININ RECEPTOR ANTAGONISTS | LABORATOIRES FOURNIER S.A. (FR) | 2005-04-13 | — | — | EP | disclosed |
| WO-2003106428-A1 | NOVEL ARYLSULPHONAMIDE DERIVATIVES AND USE THEREOF AS THERAPEUTIC AGENTS | LABORATOIRES FOURNIER SA (FR) | 2003-12-24 | — | — | WO | disclosed |