SCHEMBL6184918

SCHEMBL6184918

CC1CC(=O)N(OCc2ccccc2)C1=O

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 2/20 0.41
KCNA5 P22460 4/20 0.40
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
KDM4C Q9H3R0 1/20 0.39
MAPT P10636 2/20 0.39
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ELANE P08246 1/20 0.38
HTR2C P28335 1/20 0.38
HPGD P15428 1/20 0.37
PSEN1 P49768 1/20 0.37
PSEN2 P49810 1/20 0.37
APH1B Q8WW43 1/20 0.37
NCSTN Q92542 1/20 0.37
APH1A Q96BI3 1/20 0.37
PSENEN Q9NZ42 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4179162 1.00 ALDH1A1 (0.44) ALDH1A1TSHRKCNA5KMT2AMEN1
SCHEMBL14124969 0.85 ALDH1A1 (0.42) ALDH1A1TSHRKCNA5KMT2AMEN1
SCHEMBL4703293 0.81 ALDH1A1 (0.41) ALDH1A1TSHRKCNA5KMT2AMEN1
SCHEMBL27682102 0.81 KCNA5 (0.42) ALDH1A1TSHRKCNA5KMT2AMEN1
SCHEMBL4698180 0.81 ALDH1A1 (0.41) ALDH1A1TSHRKCNA5KMT2AMEN1
Hydrochloric Acid SCHEMBL4698115 0.80 ALDH1A1 (0.40) ALDH1A1TSHRKCNA5KMT2AMEN1
Hydrochloric Acid SCHEMBL4698117 0.80 ALDH1A1 (0.40) ALDH1A1TSHRKCNA5KMT2AMEN1
SCHEMBL10402245 0.80 KMT2A (0.52) ALDH1A1TSHRKMT2AMEN1KDM4C
Hydrochloric Acid SCHEMBL4698659 0.80 ALDH1A1 (0.40) ALDH1A1TSHRKCNA5KMT2AMEN1
SCHEMBL16577066 0.78 ALDH1A1 (0.50) ALDH1A1TSHRKCNA5KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9567302-B2 Carbamate compounds and of making and using same ABIDE THERAPEUTICS, INC. (US) 2017-02-14 US disclosed
US-9567302-B2 Carbamate compounds and of making and using same ABIDE THERAPEUTICS, INC. (US) 2017-02-14 US disclosed
US-9567302-B2 Carbamate compounds and of making and using same ABIDE THERAPEUTICS, INC. (US) 2017-02-14 US disclosed
US-20150080364-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME ABIDE THERAPEUTICS, INC. (US) 2015-03-19 US disclosed
US-20150080364-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME ABIDE THERAPEUTICS, INC. (US) 2015-03-19 US disclosed
EP-2828253-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME Abide Therapeutics, Inc. (US) 2015-01-28 EP disclosed
WO-2013142307-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME ABIDE THERAPEUTICS (US) 2013-09-26 WO disclosed
EP-1529042-A1 ARYLAMIDES Bayer HealthCare AG (DE) 2005-05-11 EP disclosed
EP-1501795-A1 CINNAMIC ACID AMIDES Bayer Aktiengesellschaft (DE) 2005-02-02 EP disclosed
WO-2004113290-A1 SUBSTITUTED ALKYLAMIDES BAYER HEALTHCARE AG (DE) 2004-12-29 WO disclosed
EP-1448521-A1 DERIVATIVES OF ANDRIMIDE AND MOIRAMIDE B HAVING ANTIBACTERIAL PROPERTIES Bayer HealthCare AG (DE) 2004-08-25 EP disclosed
WO-2004020432-A1 ARYLAMIDES BAYER HEALTHCARE AG (DE) 2004-03-11 WO disclosed
WO-2003091212-A1 CINNAMIC ACID AMIDES BAYER HEALTHCARE AG (DE) 2003-11-06 WO disclosed
WO-2003043982-A1 DERIVATIVES OF ANDRIMIDE AND MOIRAMIDE B HAVING ANTIBACTERIAL PROPERTIES BAYER HEALTHCARE AG (DE) 2003-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150080364-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME CPS1, FABP4, VHL ALDH1A1 2586/4885TSHR 1704/4885KCNA5 1719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.