Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | CGAS | Q8N884 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857411 | 0.82 | POLB (0.40) | POLBMAPTADORA1CGASADORA3 | |
| SCHEMBL4858686 | 0.82 | POLB (0.40) | POLBMAPTADORA1CGASADORA3 | |
| SCHEMBL16408073 | 0.75 | ADAMTS4 (0.36) | POLBMAPTADORA1CGASADORA3 | |
| SCHEMBL394264 | 0.72 | CPA1 (0.49) | — | |
| SCHEMBL5486443 | 0.72 | SSTR3 (0.47) | POLBMAPTCTSAMEN1KMT2A | |
| SCHEMBL6958424 | 0.71 | ADORA1 (0.39) | ADORA1ADORA3ADORA2AADORA2BKDM4E | |
| SCHEMBL1696579 | 0.71 | ADORA1 (0.47) | POLBMAPTADORA1ADORA3ADORA2A | |
| SCHEMBL21245238 | 0.71 | ADORA1 (0.43) | MAPTADORA1CGASADORA3ADORA2A | |
| SCHEMBL21245237 | 0.71 | ADORA1 (0.43) | MAPTADORA1CGASADORA3ADORA2A | |
| SCHEMBL2341611 | 0.70 | TACR3 (0.44) | MAPTADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246807-B1 | NOVEL HYDANTOIN, THIOHYDANTOIN, PYRIMIDINEDIONE AND THIOXOPYRIMIDINONE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | SOD CONSEILS RECH APPLIC (FR) | 2005-11-02 | — | — | EP | disclosed |