Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.56 |
| ▸ | ACACA | Q13085 | 16/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.40 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186970 | 0.87 | ACACB (0.54) | ACACBACACABCHEKDM2B | |
| SCHEMBL977119 | 0.86 | ACACB (0.64) | ACACBACACAL3MBTL1KDM4EMEN1 | |
| SCHEMBL6183887 | 0.84 | ACACB (0.57) | ACACBACACAL3MBTL1BCHEMBTD1 | |
| SCHEMBL6182987 | 0.80 | ACACB (0.73) | ACACBACACABCHE | |
| SCHEMBL6184795 | 0.79 | ACACB (0.61) | ACACBACACAL3MBTL1BCHEMBTD1 | |
| SCHEMBL6182739 | 0.76 | ACACB (0.72) | ACACBACACAKDM4EKDM2B | |
| SCHEMBL3465253 | 0.75 | ACACB (0.74) | ACACBACACAL3MBTL1MBTD1TP53BP1 | |
| SCHEMBL13193355 | 0.75 | ACACB (0.67) | ACACBACACAL3MBTL1MBTD1TP53BP1 | |
| SCHEMBL6183390 | 0.75 | ACACB (0.74) | ACACBACACAL3MBTL1MBTD1TP53BP1 | |
| SCHEMBL6185259 | 0.75 | ACACB (0.56) | ACACBACACABCHEKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | claimed |