Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 19/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185817 | 0.90 | BDKRB1 (0.65) | BDKRB1CNR1 | |
| SCHEMBL6481569 | 0.78 | BDKRB1 (0.51) | BDKRB1CNR1BRS3 | |
| SCHEMBL1712893 | 0.72 | BDKRB1 (0.71) | BDKRB1CNR1BRS3 | |
| SCHEMBL23354270 | 0.71 | IL2 (0.49) | BRS3 | |
| SCHEMBL6184735 | 0.69 | BDKRB1 (0.84) | BDKRB1 | |
| SCHEMBL5783737 | 0.69 | BDKRB1 (0.51) | BDKRB1CNR1 | |
| SCHEMBL1713230 | 0.68 | BDKRB1 (1.00) | BDKRB1CNR1 | |
| SCHEMBL13449215 | 0.68 | BDKRB1 (1.00) | BDKRB1CNR1 | |
| SCHEMBL1713231 | 0.67 | BDKRB1 (0.84) | BDKRB1CNR1 | |
| SCHEMBL7930737 | 0.66 | MEN1 (0.50) | BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501787-B1 | N-BIPHENYLMETHYL AMINOCYCLOALKANECARBOXAMIDE DERIVATIVES WITH A SUBSTIITUENT ON THE METHYL USEFUL AS BRADYKININ ANTAGONISTS | MERCK & CO INC (US) | 2005-11-09 | — | — | EP | claimed |