Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 18/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | BRS3 | P32247 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185817 | 0.88 | BDKRB1 (0.65) | BDKRB1CNR1 | |
| SCHEMBL5782528 | 0.83 | BDKRB1 (0.64) | BDKRB1CNR1 | |
| SCHEMBL6185353 | 0.78 | BDKRB1 (0.52) | BDKRB1CNR1BRS3 | |
| SCHEMBL6182446 | 0.75 | BDKRB1 (0.46) | BDKRB1BRS3 | |
| SCHEMBL6184891 | 0.72 | BDKRB1 (0.54) | BDKRB1BRS3 | |
| SCHEMBL6185454 | 0.72 | BDKRB1 (0.79) | BDKRB1 | |
| SCHEMBL3120001 | 0.72 | BDKRB1 (0.52) | BDKRB1BRS3 | |
| SCHEMBL1712893 | 0.70 | BDKRB1 (0.71) | BDKRB1CNR1BRS3 | |
| SCHEMBL19107200 | 0.69 | OPRM1 (0.43) | — | |
| SCHEMBL19096292 | 0.69 | OPRM1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919343-B2 | N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives | MERCK & CO., INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20030220375-A1 | N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives | MERCK SHARP & DOHME LLC | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220375-A1 | N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives | BDKRB1, BDKRB2, CNR2 | BDKRB1 1/4885CNR1 9/4885BRS3 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.